The transition from monocyte to tissue-resident macrophage requires DHPS
A cell-intrinsic, tissue-agnostic pathway that drives differentiation of monocyte-derived macrophages into RTM…
A cell-intrinsic, tissue-agnostic pathway that drives differentiation of monocyte-derived macrophages into RTM…
Obesity increased SAMHD1 phosphorylation and thereby compromised its deoxynucleoside triphosphatase function, …
The indispensable role of ARPC5-containing, but not ARPC5L-containing, Arp2/3 complexes in mononuclear phagocy…
Macrophages are key for MR1 antigen presentation and MAIT cell immunity.…
Highlights•MiTEs are novel myeloid-targeted immunocytokine prodrugs for cancer immunotherapy•TREM2 antagonis…
PU.1 expression in microglia is regulated not only genetically but also epigenetically by the microenvironment…
Capillary-associated macrophages (CAMs) are selectively lost over time, contributing to impaired vascular repa…
Efferocytosis-associated reprogramming of the islet macrophages and the subsequent influence on the adaptive i…
A targetable epigenetic node of myeloid progenitor dysregulation that sustains immunoregulatory mo-macs in the…
Highlights•Astrocyte processes reduce contact with synapses before synapse removal by microglia•Microglia-de…
Highlights•Erythroblast island (EBI) macrophages are recruited to the bone metastatic niche•EBI macrophages …
A novel mode of bidirectional microglia-neuron communication centred around GM2 ganglioside turnover, identify…
Macrophages sense deviation in intracellular pH as a mechanism to guide the control of inflammatory responses.…
Healthy tissue may be damaged by the activity of immune cells working to eradicate infection. Hoagland et al. …
AbstractAs tissue resident macrophages of the central nervous system (CNS) parenchyma, microglia perform diver…
